Collaborative efforts through international and regional workshops have played major roles in advancing HLA typing. Since 1974, the International Cell Exchange has played an important role in improving HLA typing in the interim between workshops.
The main goals are:
- Document the progress of tissue typing.
- Standardize typing of established specificities to attain international agreement.
- Identify new variants.
- Identify serologic equivalents for alleles with little or no serologic information.
- Aid developing laboratories to identify "trouble areas," such as serum screening panels and procedures.
Within the International Cell Exchange - 6 programs and International KIR Exchange:
8 shipments per year |
Per shipment |
1. |
Cell Exchange-Class I serology |
4 lymphocyte preps |
2. |
Cell Exchange-Class I DNA |
4 cell preps |
3. |
DNA Extract Exchange-Class I DNA |
4 extracts |
4. |
Serum Exchange-Class I antibody identification |
4 sera |
5. |
B-cell line Exchange- Class II serology |
2 cell lines |
6. |
B-cell line Exchange- Class II DNA |
2 cell lines |
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3 shipments per year |
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1. |
KIR Exchange |
4 extracts |
2. |
MICA Exchange |
4 extracts |
Many laboratories use our programs to fulfill their external quality control needs. In 2006, over 200 laboratories throughout the world actively participated in our exchange programs. Nearly half of the participants were laboratories outside the United States, affirming that our Exchange is truly an international collaboration.
If you wish to join, please click the "Subscription/Fees" link at the bottom of this page.
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